Apostolski S, Marinkovic Z, Nikolic A, Blagojevic D, Spasic MB, Michelson AM  J Environ Pathol Toxicol Oncol 1998;17(3-4):325-9

Institute of Neurology, School of Medicine, University of Belgrade, Yugoslavia.

The activity of glutathione peroxidase (GSH-Px) as well as the activities of other antioxidative enzymes: CuZn superoxide dismutase (CuZn SOD), catalase(CAT), glutathione reductase (GR) in erythrocytes, as well as the activityof plasma glutathione transferase (GST), and the plasma content of vitaminsE and C were evaluated in 35 sporadic amyotrophic lateral sclerosis (sALS)patients. The results revealed significantly decreased activity of both GSH-Pxand CuZn SOD in sALS patients compared with the control. These data showed that a disturbed oxidative/antioxidative balance in sALS patients exists not only in motoneurons but also in the blood. The effect of exogenously administered selenium (Se), antioxidants, amino acids, a Ca2+ channel blockersuch as nimodipine, and their combination in Alsamin was evaluated by screening parameter levels after 9 weeks of treatment. Only the use of all components together enhanced the activity of GSH-Px and the amount of vitamin E in sALS patients. Judging by the results of clinical trials, this treatment slowed the course of the disease.

Please Note

We are sorry but we can offer no international Paypal orders. These must be made by Fax. Any inadvertent international Paypal orders placed will be refunded less $20 transaction fee.

P.O. Box 1357
Sparta, NC 28675
Phone: 336-793-6524
Fax: 336-372-1541
Email: sotousa@skybest.com

Shipping Charges

$1.00 - $50.00 = $18.00
$50.01 - $100.00 = $22.00
$100.01 - $150.00 = $27.00
$150.01 - $200.00 = $32.00
Over $200 or more and orders including books ask for shipping charges