Jurige J  Personal Communication  2003

With regard to the triad usage of pharmaceutical agents Elmiron, Benadryl, and Elavil.  Dr. Jurige a Urologist in Louisville Kentucky notes: “The only FDA approved oral medication is Elmiron, which is related chemically to heparin and helps the bladder to form a new healthy lining over time.  Benadryl is useful because (interstitial cystitis) IC may have an allergy component in some patients.  Elavil cuts down on bladder spasms and pain. Other useful treatments include hydrodistention of the bladder under anesthesia with the instillation of dimethyl sulfoxide liquid into the bladder. Some patients also respond to bladder antispasmodics such as Detrol LA and Ditropan XL.  The key is that different things work for different patients and variants of the disease.  Above all, patients need an understanding and sympathetic urologist.”

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